Structural Biology of Cellular Signal Transduction and DNA Replication
John Kuriyan is interested in the construction, mechanism, and regulation of the molecular machines and switching devices that carry out signal transduction and DNA replication. His laboratory uses x-ray crystallography to determine the three-dimensional structures of the component proteins, along with biochemical and biophysical analyses to elucidate mechanisms.
Dr. Kuriyan is also Chancellor's Professor at the University of California, Berkeley. He received a B.S. degree in chemistry from Juniata College, Pennsylvania, and a Ph.D. degree from the Massachusetts Institute of Technology, where he worked with Gregory Petsko and Martin Karplus (Harvard University) on the dynamics of proteins. He continued with Martin Karplus and Greg Petsko for a year and then moved to Rockefeller as Assistant Professor and University Fellow. Dr. Kuriyan is a member of the National Academy of Sciences.